Question marks have been raised over the futures of Chris Smalling and Phil Jones as they continue to be unavailable for Manchester United.
Franco Jara scored the only goal of the match as hosts Pachuca won Wednesday's return leg 1-0 against 10-man Tigres UANL.
Tensions boiled over between Penarol and Palmeiras and both sets of fans in Montevideo.
Real Madrid midfielder Isco revelled in his stellar display at Deportivo La Coruna on Wednesday.
In his 319th appearance, Javier Mascherano scored his first goal for the LaLiga titleholders in Wednesday's 7-1 rout of Osasuna.
Real Madrid face a crucial period in their pursuit of a first LaLiga trophy since 2012, says James Rodriguez.
Zinedine Zidane had nothing but praise for Isco after he starred in the absence of Cristiano Ronaldo and Gareth Bale away from home.
Borussia Dortmund coach Thomas Tuchel was understandably delighted with his side's DFB-Pokal win over rivals Bayern Munich.
Relegation-threatened Sunderland deserved something from their 1-0 defeat at Middlesbrough, insists David Moyes.
Alexis Sanchez's histrionics were perhaps the most memorable moment from Arsenal's Premier League clash with Leicester City.
Following an injury in defeat to Tottenham, Crystal Palace boss Sam Allardyce was keen for an update on loan star Mamadou Sakho's fitness.
The north London derby rarely fails to disappoint and Sol Campbell expects a particularly fierce battle when Tottenham entertain Arsenal.
Ahead of a derby with Arsenal on Sunday, Mauricio Pochettino was delighted to see Tottenham keep their title chase going with another win.
Arsene Wenger has talked up Arsenal's chances of finishing in the Premier League's top four following their 1-0 victory over Leicester City.
Hoping Malaga beat Real Madrid on LaLiga's final day is not how Luis Enrique plans leading Barcelona to the title.
Bayern Munich coach Carlo Ancelotti rued his side's missed chances after they were beaten 3-2 by rivals Borussia Dortmund.
Manchester City boss Pep Guardiola retains optimism for the future as his side approach the derby against United with no hope of trophies.
Manchester United midfielder Paul Pogba will miss the derby against City, but left a telling impression on Pep Guardiola.
Although Tottenham again closed the gap to Chelsea in the title race, Harry Kane insists his side are focused only on their own fortunes.
A much-changed Real Madrid had too much for Deportivo La Coruna as they ran out 6-2 winners at Riazor to go level with leaders Barcelona.